Metformin and nitrosamine impurities
نویسندگان
چکیده
منابع مشابه
Nutrition and nitrosamine formation.
Nutrition and the fmmation of N-nitroso compounds N-nitroso compounds are an important group of chemical carcinogens that could be involved in human cancer (Magee, 1982). Only a few examples have been found in food and beverages (Assembly of Life Sciences, 1981) but suitable precursors are common dietary constituents (Assembly of Life Sciences, 1981), and the mildly acidic conditions of the sto...
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Previous studies have shown that a diet high in fat and marginally deficient in lipotropes enhances aflatoxin B] hepatocarcinogenesis and depresses hepatic drug metabolism in rats. In this study we have compared induction of tumors by jV-nitrosodimethylamine, ./V-nitrosodiethylamine, or jV-nitrosodibutylamine in normal or marginally lipotrope-deficient rats fed a high-fat diet. The deficiency s...
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The interest in the carcinogenic and biological actions of N-nitroso compounds arose following the reports of the hepatotoxicity by Freund' and Barnes and Magee2 and ofcarcinogenicity (Magee and Barnes)3 of the simplest nitrosamine: N-nitrosodimethylamine (dimethylnitrosamine) and the subsequent observation of Schoental4 and Druckrey et aP on the carcinogenic action of the nitrosamides: n-methy...
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We describe the BPS dynamics of vortices in the presence of impurities. We argue that a moduli space of solitons survives the addition of both electric and magnetic impurities. However, dynamics on the moduli space is altered. In the case of electric impurities, the metric remains unchanged but the dynamics is accompanied by a connection term, acting as an effective magnetic field over the modu...
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most versatile and sensitive tools for micro-chemical studies of biological material. Since the publication of Volume I, which covers this topic very briefly, many advances have been made both in the development of new procedures and in the adaptation of existing ones to the micro-chemical level. Although the latter deficit is recognized by Dr. Glick in the preface to Volume II, it is unfortuna...
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ژورنال
عنوان ژورنال: International Journal of Research in Medical Sciences
سال: 2020
ISSN: 2320-6012,2320-6071
DOI: 10.18203/2320-6012.ijrms20204273